Abstract During Central Nervous System ontogenesis. myelinating oligodendrocytes (OLs) arise from highly ramified and proliferative precursors called oligodendrocyte progenitor cells (OPCs). OPC architecture. proliferation and oligodendro-/myelino-genesis are finely regulated by the interplay of cell-intrinsic and extrinsic factors. https://www.angelswithheart.com/product-category/skincare-and-beauty-products/